tfmindi.load_motif_to_dbd

tfmindi.load_motif_to_dbd(motif_annotations)

Create motif-to-DNA-binding-domain mapping for human TFs.

Takes motif annotations and maps motifs to their DNA-binding domains based on TF annotations and human TF database information.

Parameters:

motif_annotations (DataFrame) – DataFrame with motif annotations as returned by load_motif_annotations()

Return type:

dict[str, str]

Returns:

dict[str, str] Dictionary mapping motif IDs to DNA-binding domain names

Examples

>>> annotations_file = fetch_motif_annotations("hgnc", "v10nr_clust")
>>> motif_annotations = load_motif_annotations(annotations_file)
>>> motif_to_dbd = load_motif_to_dbd(motif_annotations)
>>> print(motif_to_dbd["hocomoco__FOXO1_HUMAN.H11MO.0.A"])
'Forkhead'